Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Article

J App Pharm Sci. 2016; 6(5): 073-079

Phytochemistry and in vitro Antimicrobial, Antioxydant Activities of Entandrophragma candollei H.

Nnanga NGA, Vandi Deli, Famen NDEL Louis Claire, SIDJUI SIDJUI Lazare, SIKADEU Sandrine, NGUE Samuel Arthur, Toghueo Kouipou Rufin Marie, Nganso DITCHOU Yves Oscar, MPONDO MPONDO Emmanuel.

The research work was conducted to investigate the in vitro antimicrobial and antioxidant activity of extract of E .candollei (Family-Meliaceae).Phytochemical screening was done.Disc diffusion technique was used for in vitro antibacterial and antifungal screening. Minimal inhibitory concentration of promising extracts was determined by broth microdilution method. The phytochemical screening showed the presence of flavonoids compounds, tannins and saponins. The inhibition diameters were ranging from 7 to 17 mm and Minimum Inhibitory Concentrations (MIC) from 156.25 to 2500 g/mL. The ethyl acetate and ethanolic extract revealed a high radical scavenging activity with IC50 ranging from 9.1026 to 11.8298 g/mL. The Ferric reducing power activity was obtained with active concentration ranging from 12.5 to 200 g/mL. These results suggest that extracts from E. candollei possess antibacterial and antioxidant activities and therefore justifies their usagein traditional medicine for the treatment of various diseases.

Key words: Entandrophragma candollei, antioxidant, antimicrobial activity

Full-text options

Full-text Article

American Journal of Diagnostic Imaging


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.