Home|Journals|Articles by Year|Audio Abstracts
 

Original Article

J App Pharm Sci. 2015; 5(10): 147-150


Antibacterial and antioxidant activities of methanolic leaf extract of Maerua crassifolia

Kingsley Chimsorom Ckilaka, Godwin Christian Akuodor, Joseph Linus Akpan, Emeka Daniel Ogiji, Chukwuemeka Okorie Eze, Basil Chukwuma Ezeokpo.




Abstract

The objective of this study was to investigate the antibacterial and antioxidant activities of the methanol leaf extract of Maerua crssifolia, an important medicinal plant used in Nigeria. The antibacterial properties of the methanol extract were studied against clinically important bacteria viz; Staphylococcus aureus, Shigella spp., Salmonella typhi, Bacillus subtilis and Escherichia coli by disc diffusion method. The free radical scavenging potential of the extract was assessed by measuring its capability for scavenging 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical. The methanol leaf extract of Maerua crssifolia at the concentration of 12.5-150 µg/ml, showed significant activity against all the tested organisms. The observed antioxidant activity of the leaf extract suggests that the extract is a potential source of natural antioxidant and could be useful in the treatment of diseases.

Key words: Maerua crassifolia, leaf extract, methanol, antibacterial agent, DPPH, antioxidant.






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.