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Original Research

Med Arch. 2010; 64(4): 204-207


Cerebrovascular Events: Correlation with Plaque Type, Velocity Parameters and Multiple Risk Factors

Mirza Dilic, Mehmed Kulic, Sefkija Balic, Alen Dzubur, Amel Hadzimehmedagic, Haris Vranic, Suada Svrakic.




Abstract

Purpose: Cerebrovascular events (CVE) are the third most common cause of death in Western countries and about 65-70% of CVE are due to atherosclerotic disease of carotid arteries. Color Doppler scanning is used to evaluate the presence, severity and type of atheromatous plaques as well as velocity parameters of carotid arteries. We performed this study to correlate data of morphological and velocity parameters with clinical variables in patients following CVE. Methods: We included total of 211 pts who had CVE, 118 females, 93 males, mean age 71,1± SD 12,5 years. Out of total number of pts (n=211) 93 pts had transient ischemic attacks (TIAs), 49 had recurrent TIAs (rTIAs), 44 had ischemic stroke (IS), and 25 had recurrent IS (rIS). As a control group we took 50 pts without CVE but with at least three multiple risk factor (MRF). Morphological parameters were; plaque composition and echogenecity. Velocity parameters were: peak-systolic velocity (PSV) and end-diastolic velocity (EDV). The following MRF were evaluated: age, gender, hypertension, tobacco smoking, hyperlipidemia (total cholesterol and LDL-cholesterol), obesity, and diabetes mellitus. Examination was performed on CCA/ICA segment. Results: We found significant presence of heterogeneous plaques in TIAs and rIS subgroup, p

Key words: Key words: cerebrovascular events, symptomatic carotid disease, plaque, velocity parameters, risk factors






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