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Original Research

Nig. Vet. J.. 2018; 39(2): -


COMPARISON OF BLOOD BIOCHEMISTRY RESPONSES OF COCKERELS AND TURKEYS EXPERIMENTALLY INFECTED WITH A VELOGENIC NEWCASTLE DISEASE VIRUS

Obianuju N. Okoroafor, Christian Onwuchokwe Okorie-Kanu, Paul C. Animoke, John A. O Okoye, John A. Nwanta, Boniface M. Anene.


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Abstract
This study compared the serum biochemical responses of cockerels and turkeys infected with a velogenic Newcastle disease virus (NDV). Two hundred and fourty birds of one hundred and twenty each were used for the study. The birds were obtained at day-old and were randomly divided into eight groups of four groups for each bird species. Two groups from both bird types were vaccinated against NDV with La Sota vaccine at three weeks of age. The vaccinated and unvaccinated cockerels and turkeys were subsequently inoculated with the velogenic NDV after six weeks while the control groups were not vaccinated and not inoculated. Blood samples were randomly collected from five birds in each group for serum biochemical analyses at days 0, 3, 6, 10, 15 and 21 post inoculation (pi). Parameters determined included serum alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase activities, total serum proteins, albumin, globulin, blood glucose level, total cholesterol, blood urea nitrogen and creatinine. Data generated were analyzed using one-way analysis of variance (ANOVA). Results showed decreased (p

Key words: Blood biochemistry, Velogenic NDV, Cockerels, Turkeys


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