Objective: To retrospectively analyze post renal transplant patients to see the frequency of CMV infection, risk factors, its prevention and treatment at our Institutution.
Methodology: This study was done from January 2008 to January 2017 at Institute of Kidney Diseases, Peshawar, Pakistan. Clinical records and laboratory data were collected. CMV viral load was monitored by CMV quantitative nucleic acid testing.
Results: A total of 200 patients with 178 male and 22 females were studied. The frequency of CMC was 13.5 % (27 patients). All of these were seen after 3 months of renal transplantation.
Conclusions: The CMV infection is more common in patients with intense post renal transplant immunosuppression with induction therapy. Ganciclovir is an effective treatment against CMV infection. All patients who receive induction therapy must be given ganciclovir as a prophylaxis. Frequent CMV PCR should be done post prophylaxis where there is increase chance of CMV vireamia.
Key words: Cytomegalovirus, kidney transplantation, ganciclovir
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