Objective: To highlight the degree of importance of using this test in heat stroke as diagnostic tool and its role in assessing worsening prognosis with rising CPK level or otherwise.
Methodology: Total of 78 patients admitted in Department of Medicine, JPMC, Karachi, Pakistan during 3 days from June 21st to 23rd 2015 when heat wave struck Karachi were included in the study. The patient who survived 1st hour after receiving intense ICU management underwent this laboratory test.
Result: Out of 78 patients, 51 (65.3%) were male and 27 (34.6%) female. The mortality rate was 53.8% (n=42); 33 (78.8%) were above 50 years and 9(33.3%) below 50 years. 55(70.5%) patients who survived 1st hour, were found to have raised CPK which was associated with 36.3% (n=20) mortality in patient with CPK >1000.
Conclusion: CPK, despite being non specific can be a valuable tool for diagnosis and assessing the prognosis of heat stroke patients.
Key words: Creatinine phosphokinase, heat stroke, Karachi.
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