Home|Journals|Articles by Year|Audio Abstracts
 

Original Article

J App Pharm Sci. 2017; 7(1): 086-092


Synthesis and characterization of cobalt ferrites nanoparticles with cytotoxic and antimicrobial properties

Amal S. Hathout, Abdulhadi Aljawish, Bassem A. Sabry, Aziza A. El-Nekeety, Mohamed H. Roby, Nasseralla M. Deraz, Soher E. Aly, Mosaad A. Abdel-Wahhab.




Abstract

Recently, the application of nanotechnology in food sector and the agriculture attract the attention compared to its biomedical application. The aims of the current study were to synthesize and characterize cobalt ferrites nanoparticles [(CoFe2O4) NPs] by combustion method employing glycine as fuels and to evaluate their antimicrobial against pathogenic bacteria and fungi and anti cancer properties against MCF-7 breast cancer cells line. The results indicated that the particles size of the synthesized (CoFe2O4) NPs was 40 nm. These (CoFe2O4) NPs showed potential antibacterial properties against Gram-negative bacteria (Escherichia coli, Salmonella typhi) and Gram-positive bacteria (Staphylococcus aureus, Bacillus cereus) as well as the pathogenic fungi (Aspergillus flavus and Aspergillus ochraceus) in a dose dependent manner with maximum concentration of 1.8 mg/ml. (CoFe2O4) NPs also showed weak antiradical but have cytotoxic effects against MCF-7 breast cancer cells line and succeeded to decrease the cell viability at a concentration of 2 mg/ml. it could be concluded that (CoFe2O4) NPs is a promise candidate as antimicrobial and anticancer agent for food sector and medical application.

Key words: Food safety; antimicrobial; anticancer; cobalt ferrites nanoparticles; nanotechnology






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.