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Original Article

Med Arch. 2016; 70(5): 348-350


Association of Beta-2 Microglobulin with Inflammation and Dislipidemia in High-Flux Membrane Hemodialysis Patients

Valdete Topçiu–Shufta, Ramë Miftari, Valdete Haxhibeqiri, Shpend Haxhibeqiri.




Abstract

Background: Higher than expected cardiovascular mortality in hemodialysis patients, has been attributed to dyslipidemia as well as inflammation. Beta2-Microglobulin (β2M) is an independent predictor of outcome for hemodialysis patients and a representative substance of middle molecules. Results: In 40 patients in high-flux membrane hemodialysis, we found negative correlation of β2M with high density lipoprotein (r=-0.73, p

Key words: hemodialysis, beta-2 microglobulin, inflammation, dyslipidemia, cardiovascular diseases






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