Peripheral edema is associated with multiple medical etiologies (systemic disorders, hypoproteinemia, long-term immobility, cancer diseases) and drugs (nonsteroidal anti-inflammatory drugs, antihypertensives, steroids, and immunsupressive agents). Olanzapine is an atypical antipsychotic medication approved for treatment of schizophrenia, bipolar affective disorder and other psychiatric disorder. Olanzapine-induced side effects is also presented with weight gain, drowsiness, asthenia, constipation, dyspepsia, dry mouth, and dizziness. Olanzapine-induced edema formation mechanisms at the level of information about the ongoing assumptions and olanzapine-induced receptor is reported to be associated with the profile. In this case report, a case of olanzapine-induced peripheral edema, not known more than the other side effects of olanzapine has been presented and probable mechanisms of edema has been discussed.
Key words: olanzapine, peripheral edema, atypic antipsychotics, side effects
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