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Case Report

Ann Med Res. 2015; 22(1): 34-36


Antagonism of the Effect of Rocuronium with Sugammadex in a Patient with Myasthenia Gravis

Vahap Saricicek, Mehrican Sahin, Cigdem Kadi, Ayse Mizrak, Mehmet Cesur.




Abstract

Myasthenia Gravis (MG) is an autoimmune disorder which is characterized by the decrease of number, function, and capacity of ach
receptors in muscle-nerve junctions. Anaesthesia is important patients with MG especially when they need muscle relaxants, which is a risky
condition due to the possibility of postoperative residual neuromuscular blockage. Before the discovery of Sugammadex, colinesterase
inhibitors were used to reverse the effects of non-depolarising muscle relaxants to treat MG patients. In these cases, practitioners had to
deal with several side effects in MG patients. Sugammadex encapsules the steroid structured muscle relaxants and immediately reverses
their effects. Therefore, anaesthesiologists started to use Sugammadex to decrease the need of postoperative residual blockage and
mechanical ventilation. In this case report, we aim to share our experiences of Sugammadex use and relate readers how it eliminated the
effect of rocuronium in an MG patient who underwent VATS.

Key words: Myasthenia Gravis; Rocuronium; Sugammadex.






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