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Original Research

Ann Med Res. 2004; 11(3): 155-159


Clinical Significance of Prophyylaxis for Thromboemboli in Hospitalized Patients

Özkan Kızkın*, Süleyman Savaş Hacıevliyagil*, Hakan Günen*

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Abstract


 

Objective: Although, there are methods recommended with consensus all over the world for the prophylaxis of

deep venous thrombosis (DVT) and pulmonary embolus (PE), these principles of prophylaxis may be neglected in

clinical practice.

Materials and Methods: This study was performed to investigate the neglected prophylaxis in patients who were

transferred to our clinics after the development of PE at the hospital and in floor patients with risk factors. Patients,

who were hospitalized for other reasons, developed PE, and were risky for VTE were included in the study. Charts

of the patients with PE (n=21) were reviewed retrospectively, and those of the patients with risk factors for VTE

(n=74) were reviewed prospectively.

Results: Sixteen patients with PE were female and 5 were male. Their mean age was 44,2±14,4 years. Although they

have been hospitalized for 12,6±10,7 days and their mean risk factor was 2,3 (1-4), none of them were on

prophylaxis. Most frequent risk factors were operation (27,1%), elderliness (25%) and trauma (10,4%).

Of the 74 patients with one or more risk factors for VTE, 43 were in surgery department, 7 were in internal

medicine floor and 17 were in the intensive care unit. Their mean duration of hospitalization, mean age and mean

risk factor number were 15,2±8,9 days, 48,7±18,1 years and 2,7 (1-6) risk factors respectively. Only 17 of them

(23%) were on prophylaxis for VTE. Most common administration of prophylaxis was noted in intensive care

clinics (52,9%) whose mean risk factor was highest (2,9%), and the least prophylaxis was noted in obstetric and

gynecology clinics (7,1%).

Conclusion: Although PE is an important reason for the in-hospital mortality, prophylaxis for VTE has not been

administered sufficiently. We think that, in case of sufficient administration of prophylaxis especially for patients


with risk factors, development of VTE and/or PE incidence and their attributable morbidity and mortality will decrease.

Key Words: Deep vein thrombosis, Pulmonary emboli, Prophylaxis.







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