The present study aimed to evaluate the effects of isothermal non-ionizing electromagnetic fields (EMFs) on the liver of mice. The mice were exposed to man-made visible light with intensity 77 mW/cm2 on the area of 72.5 cm2 and frequency of electromagnetic radiation between 3.9 x 1014 Hz and 7.5 x 1014 Hz W/ cm2 for 8 hours/day for 3, 6, and 12 days. The present results indicated that exposing mice to visible light for 3 days showed no histopathological signs in the liver. Six and 12 days of exposure to EMFs showed marked distortion and disorganization of hepatic tissues. Many apoptotic hepatocytes, focal necrosis, hypertrophied binuclei, dilated the hepatic sinusoids, and destruction of bile ductules were noticed. Moreover, total polysaccharides and total proteins decreased in the hepatocytes of treated animals. In conclusion, man-made visible light radiation, represented with the commonly used neon lamps, affects negatively on the liver tissue of male mice.
Key words: Electromagnetic fields, Liver, Mice, Histopathology
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