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Review Article

SRP. 2020; 11(3): 532-537

Analysis of Influence of External and Internal Environment Factors on Pharmacy Production of Infusion Medicinal Drugs

Andrey Borisovich Goryachev, Taisiya Ivanovna Kabakova, Ivan Ivanovich Krasnyuk (j& 1082;), Natal'ya Nikolaevna Kuvshinova, Elena Yur'evna Lemeshchenko, Oleg Nikolaevich Afanas'ev, Sergey Borisovich Davidov.


Background. Amid a reduction in the number of pharmacy organizations that have licenses to manufacture medicinal drugs, including in aseptic conditions, there is a need to analyze the reasons that hinder the improvement of the production function of pharmacies, aimed at improving the availability of medical care to patients of multidisciplinary medical organizations.
Objective. The objective of the work was to analyze the influence of external and internal environment factors on the organization of production activity of pharmacies of multidisciplinary medical organizations and to develop proposals to improve the organization of pharmacy manufacturing of medicinal drugs on the example of infusion solutions.
Methods. PEST-analysis method has been used as an instrument of scientific analysis of the influence of external and internal environment factors on the pharmaceutical production of medicinal drugs in a multidisciplinary medical organization.
Findings. On the example of pharmacy manufacturing of infusion medicinal drugs it has been established that the greatest influence on restraining the progressive development of the technological process is exerted by technological factors associated with the lack of modern effective equipment of production processes, in which the main provisions and requirements of good manufacturing practice (GoodManufacturingPractice - GMP) are structurally realized. The second most important place is occupied by a group of economic factors, which increases the economic attractiveness of manufacturing the most demanded range of medicinal drugs for the needs of the medical organization, which allows quite realistically, from the point of view of return on investment, to consider the modernization of the technological process of pharmacy manufacturing of medicinal drugs. The third place is occupied by political factors related to institutional issues of regulating the production activities of pharmacies. Social factors came in fourth place. They reflect the opinion of pharmaceutical workers, as they are responsible for the labor-intensive technological process and the output.
Conclusions. The research made it possible to outline the range of urgent tasks on improving institutional and organizational and technological approaches aimed at improving the efficiency and quality of production activities of pharmacies, as one of the reserves to improve the availability of medical care to patients of multidisciplinary medical organizations.

Key words: medicinal drugs, infusion solutions, pharmacy manufacturing, expert evaluation, external and internal environmental factors.

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