The microelements are an integral component of glucose homeostasis and other catalytic reactions. Serum concentrations of various micronutrients are associated with glycosylated hemoglobin (HbA1c) levels and complications of diabetes. The present study compares the serum concentrations of copper (Cu), chromium (Cr), and selenium (Se) in diabetic patients and nondiabetic controls and also assessed the correlation of serum Cu, Cr, and Se concentrations with HbA1c levels. The study population included 126 cases and 126 controls in a 1:1 ratio with the mean age of 56 years. Auto analyzers analyzed trace elements and HbA1c with the standard procedures. Lipid levels, including total cholesterol, high and low-density lipids, were significantly high in diabetic patients than controls (p-value
Key words: Trace elements, Micronutrients, Diabetes mellitus, Oxidative stress, Diabetic complications
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