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A prospective observational study on management and outcome of different poisoning cases in a tertiary care hospital

Vanishree B, Naga Priyanka Aramalla, Shailendra D.


Background: Acute poisoning is a worldwide health problem hastened around million deaths yearly. It was estimated that two lakhs of these deaths are mainly due to Organophosphorus compounds (OPC) poisoning. The management of these emergencies poisoning cases is very difficult and requires intensive care as well as monitoring. Despite the large number, evidence on pattern prevalence, management and outcome in India is little.

Aim and Objective: The purpose of our study was to assess the socio-demographic pattern of various poisonings, pharmacotherapy and factors associated with outcome in a tertiary care hospital.

Materials and Methods: It is a prospective observational study was done from January 2014 to December 2014 at Casualty in government teaching medical college hospital.

Results: 253 patients were identified to have suffered of poisoning, 47.0% (119) of these patients were poisoned by OPC followed by other poison such as pyrethroids, Organocabamates. From all assessed cases male over female dominance was observed. More poisoning cases were observed between the age group 21 and 30 years. Intentional poisoning was more common (87.74%). The time taken between the poison ingestion and treatment was found that 83.8% of patients introduced to hospital before 12 h of the incident, whereas 28.7% introduced before 3 h. The death rate was 1.97 % with male dominance.

Conclusion: This study comes to a conclusion that there is load of poisoning for which some proper safety measures such as limitation of easy availability and securing the poisonous chemicals which reduce the incidence of different poisoning in susceptible patients.

Key words: Acute Poisoning; Treatment Outcomes; Mortality

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