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Original Article

. 2019; 10(4): 87-91

Serum Lactate – A Prognostic Marker of Early Post-Operative Outcome After Off Pump Coronary Artery Bypass Surgery: A Propensity Matched Study

Ganesh Kumar K Ammannaya, Prashant Mishra, Jayant V Khandekar.

Objectives: Elevated blood lactate levels after on pump coronary artery bypass grafting is known to be an adverse prognostic
marker. We proposed to assess the association between hyperlactatemia and early post-operative outcome after off pump
coronary artery bypass (OPCAB) surgery.
Materials and Methods: 350 consecutive patients undergoing OPCAB surgery were studied retrospectively. Early postoperative
serum lactate level was measured in all patients, upon shifting the patient to the ICU (0 hours), at 6 hours and 12 hours. The
primary outcome was a composite of 30day all-cause mortality and severe morbidity. A propensity model was constructed to
overcome the baseline differences between the group with and without complications.
Results: 32 (9.14%) patients had at least 1 complication, which was associated with significantly prolonged mechanical
ventilation (38.6 h vs 12.8 h; p

Key words: Lactate; off pump coronary artery bypass (OPCAB) surgery; post-operative.

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