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Original Article

. 2019; 10(3): 94-98


Effects of Diabetes Mellitus on Interventional Outcome in Patients with Non-ST-Myocardial Infarction

Hala Gouda Abomandour, Hanan Ibrahim Radwan.

Abstract
Introduction: Patients with Non ST elevation myocardial infarction , the incidence of heart failure was twice in diabetic versus
non diabetic ones1,2.There is positive correlation between diabetes mellitus duration and the risk of developing acute coronary
syndromes3, An independent relation between the duration of diabetes mellitus and critically and fatal coronary artery disease
has been shown in men4, Some studies suggest that coronary artery disease and HbA1c level are predictors of cardiovascular
morbidity and mortality5. Aim of the study: To study the interventional outcomes of high-risk non-ST elevation acute myocardial
in diabetic and non-diabetic patients. Patients and methods: a prospective study was conducted in, Zagazig University Hospitals
, it included 480 patients , diagnosed by ECG, cardiac biomarker and Grace Score6 as high risk NSTE-ACS , divided into (272
Diabetic and 208 Non-diabetic).Patients were classified according to GRACE score into 3 categories high (>140), intermediate
(70140), and low (1-70), the patients underwent early emergency, or elective coronary angiography within 3 days of admission.
After intervention (PCI) , followed up for 48 hours to detect complications and death. Results: There was no significant difference
between the two groups as regard age and hypertension. Gensini and Grace scores were significantly higher in diabetes. In
patients of high Gensini and syntax scores only diabetes was an independent predictor of the extent and severity of coronary
artery obstruction. Conclusion: Diabetes Mellitus has a significant correlation with angiographic complexity and interventional
outcome in patients with Non-ST elevation myocardial infarction.

Key words: Diabetes Mellitus, Non-ST elevation myocardial infarction



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