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Case Report

JCDR. 2016; 7(2): 93-96

Clozapine-Induced Perimyocarditis

Khalil Murad, Selome G Gezahegn, Ashenafi M Tamene, Jian-Ming Li.


Atypical antipsychotic drugs are widely used in the treatment of schizophrenia
due to their higher efficacy and better side-effect profile compared
with traditional antipsychotic drugs. However, serious cardiac toxicity of
these drugs can occur, and if not recognized early, can be fatal. In this report,
we present a case of acute perimyocarditis following the initiation of
Clozapine, a frequently used atypical antipsychotic drug, for the treatment
of refractory schizophrenia, which completely resolved after the discontinuation
of this drug.

Key words: Clozapine, Atypical antipsychotic drug, Perimyocarditis

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