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Review Article

. 2015; 6(1): 24-27

Periodontitis as a Risk Factor for Cardiovascular Diseases- Hype or a Fact?

Kritika Jangid, Jayakumar Nadathur Doraiswamy, Sheeja Varghese and Sankari Malaiappan.

Background: The relationship between periodontitis and cardiovascular diseases has been a debatable topic since over a
century, yet the debate is still ongoing. Periodontitis and coronary artery disease are both immuno- inflammatory in origin
with many confounding risk factors associated with each other. Various epidemiological and interventional studies have
been carried out to prove its biologic plausibility. There is however deficient literature on the exact pathophysiology of the
spread of periodontal disease to cardiovascular disease. Objective: This review article aims to highlight on the most recent
scientific evidence to substantiate on the causal relationship between the two diseases. Results: Various interventional
and epidemiological studies suggest that there is a strong correlation between periodontitis and cardiovascular diseases,
however there is a lacunae in literature in the in-vitro and long term clinical trials to support its exact biological mechanism.
Conclusion: In the interest of public health, the cardiologists and the periodontists at large should be made to understand
the role of maintaining good oral hygiene for general well being and refer to the specialist when necessary.

Key words: Cardiovascular Disease, Focal infection, Focal Sepsis, Heart Disease, Periodontitis.

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