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Case Report

JCDR. 2013; 4(1): 58-60

Reversible myocardial dysfunction following intraocular bevacizumab administration

Srikanth C. Penumetsa, Mohammad Z. Hoque, Gregory Giugliano.


Heart failure has been reported as a rare side effect of bevacizumab, a chemotherapeutic agent, used in
the treatment of breast cancer. However, reversible left ventricular systolic dysfunction with a pattern
similar to stress-induced cardiomyopathy has not been reported. The etiopathogenesis of stress-induced
cardiomyopathy is poorly understood. Given this uncertainty, we should always look out for other
potential offenders causing similar presentation, rather than label all of them as “stress-induced”.

Key words: Bevacizumab,Heart failure,Stress-induced cardiomyopathy

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