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Case Series

Anaesth. pain intensive care. 2022; 26(6): 807-810


Case Series of Vaccinated Critical Covid 19 Patients: Clinical Characteristics and Outcomes from Low Middle-Income Country

Moeed Bin Abdul Ghaffar, Muhammad Mehmood Alam, Waleed Bin Ghaffar, Muhammad Faisal Khan, Muhammad Muhammad.




Abstract

Background: Vaccination plays an important role in the prevention of some infectious diseases but did it change the outcome in critically ill patients is obscure. Though vaccination leads to decreased emergency and hospital admission. Still, vaccinated patients with severe diseases requiring intensive care are being reported. This case series reports the outcome of 20 critically ill patients, who got admitted to the Intensive Care Unit (ICU).

Methods: All vaccinated patients admitted to COVID-ICU at the University Hospital between January 2021 and June 2021 were reviewed. The demographics, comorbidities, vaccination status, systemic manifestations, organ support, complications, pharmacological therapy, outcome and length of ICU & hospital stay were recorded. To draw a comparison for all the demographics and clinical characteristics of patients, stratification analysis was performed for the outcome variables.

Results: A total of 20 patients were included in the study among which only 7 (35%) survived. The mortality rate for patients over 60 was 84.6 %. There were only four patients with no comorbidities, and all of them survived. Among the complications, acute kidney injury was the most common (70%). The median (IQR) ICU stay was 10 days (7) and hospital stay was 13.5 days (11).

Conclusions: The vaccinated patients admitted with Critical Covid-19 had a poor outcome and irrespective of the type of vaccine. The factors leading to increased mortality in this group of patients were male gender, age ≥ 60 years, and chronic medical illness.

Key words: COVID-19, COVID-19 Vaccines; Critical Care Outcomes; Healthcare-Associated Pneumonia; Respiratory Insufficiency






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