The study evaluated the effect of sub-anaesthetic ketamine on peri-operative pain in goats anaesthesized with diazepam-ketamine prior to rumenotomy. Nine West African dwarf goats used for the study were divided into three (3) groups (n=3). Group 1 received diazepam (0.5mg/kg IV) and ketamine (5mg/kg IV), group 2 received diazepam (0.5mg/kg IV), ketamine (5mg/kg IV) and continuous IV infusion (CRI) ketamine (20µg/kg/min) 30 minutes prior to rumenotomy and group 3 received diazepam (0.5mg/kg IV), ketamine (5mg/kg IV) and CRI ketamine (20µg/kg/min) followed by rumenotomy immediately. The mean rank pain scores of CRI ketamine groups 2 and 3 were lower than that of group 1 (control) during incision of rumen and suturing of skin, muscle and rumen. There were no significant difference in mean rank pain scores during incision of skin (P=0.239), muscle (P=0.76), peritoneum (P=1.0) and rumen (P=0.083). Mean rank pain scores of the groups were not significantly different during suturing of skin (P= 0.064) and muscle (P=0.064) but significantly different during rumen suturing (P=0.004). Respiratory rate (RR) of group 1 was significantly (p
Key words: Diazepam, Ketamine, Pain, Rumenotomy, Sub-anaesthetic
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