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Case Report

Sudan J Paed. 2022; 22(1): 104-108


Protein S deficiency in an adolescent female with disseminated tuberculosis presenting as deep vein thrombosis: Confounder or correlation?

Najeeb Ahmad, Swathi Chacham, Avinish Singh, Lourembam Radha Pyari, Manish Kumar.




Abstract

Tuberculosis remains as an infectious disease with a very high prevalence in the Indian subcontinent. Deep vein thrombosis in tuberculosis is due to the increased fibrinogen levels, release of inflammatory cytokines and decreased synthesis of anti-coagulant proteins. We describe a case of deep venous thrombosis of bilateral lower limbs in association with pulmonary tuberculosis and protein S deficiency.

Key words: Deep vein thrombosis, tuberculosis, protein S deficiency, congenital.






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