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Comparative colour doppler study of lower limb deep venous thrombosis in diabetic and non diabetic patients with review of current knowledge

Bhanupriya Singh, Harsha Gara, Mridu Singh, Gaurav Raj, James Marak.




Abstract
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Introduction: The present study compared the clinical characteristics of DVT patients with and without DM. The risk of venous thromboembolism appears to be elevated in type 1 and type 2 diabetic patients. Hyperinsulinemia, often present in type 2 diabetes, has also been shown to have a prothrombotic effect. Doppler ultrasonography is a reliable, non-invasive and rapid investigation to detect DVT. Therefore helping in the early detection of DVT in clinically suspected patients. On USG, findings in favour of DVT are non-compressible venous segment with loss of phasic flow on Valsalva, shows absent colour flow if completely occlusive, and lack of flow augmentation with calf squeeze and increased flow in superficial veins.
Objectives: To assess and analyze the colour Doppler findings and evaluate the site, extent and stage of lower limb deep vein thrombosis in diabetic and non-diabetic patients.
Methods: Present observational comparative study was conducted in the Department of Radio-diagnosis of tertiary level care.
Results: A total of 36 patients were enrolled in this study 21 were diabetic, and 15 were non-diabetic. The incidence of DVT was found to be 21% among diabetics and 15% among non-diabetics.
Conclusion: The incidence of deep vein thrombosis in diabetic and non-diabetic patients differs. However, it is not statistically significant. Anatomic localization of the thrombus revealed that common iliac, external iliac, common femoral, femoral and popliteal vein involvement was more common among diabetics as compared to non-diabetics.

Key words: Diabetes mellitus, Non-diabetes mellitus, Deep vein thrombosis, venous thromboembolism






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