Abstract

Bacterial resistance was the consequence of empirical therapy and poor compliance, and its amelioration was difficult. In both in-patients and out-patients, definitive therapy resulted in better outcomes for urinary tract infections (UTI). Our objective was to identify the prevalence and to assess the susceptibility pattern of uropathogens toward antibiotics. It is a prospective, cross-sectional study conducted during the period of November, 01, 2019 to April, 28, 2020. A total of 200 UTI patient’s antibiotic susceptibility pattern was analyzed of which, 105 were males and 95 were females. Among them, 147 were in-patients and 53 were out-patients. The prevalence of UTI was high between the ages of 40 and 79 years. Less than 20% susceptibility was noticed in 20–39 years of age groups and less than 10% were observed in 80–99 years of age groups. The antibiotic susceptibility was found to be 35%–40% among the 40–59 years of age group, of them Ertapenem and Trimethoprime (TMP) & Sulfamethoxazole (SMZ) only has 48.5% and 44.6% of susceptibility and literally poor in 80–99 years. Colistin and Amikacin showed higher susceptibility toward Escherichia coli and Klebsiella pneumoniae in in-patients. The remaining antibiotics showed 40%–67% of susceptibility. TMP and SMZ, Amoxicillin Clavulanic acid, Cefoperazone, and Amoxicillin plus Clavulanic acid had relatively low susceptibility (16%–27%). Colistin, Amikacin, and Nitrofurantoin showed better susceptibility in in-patients and in out-patients. TMP and SMZ, Amoxicillin Clavulanic acid, Cefoperazone, and Amoxicillin plus Clavulanic acid had relatively low susceptibility. Escherichia coli was more prevalent Gram-negative bacteria isolated among the individuals and 57.8% of In-patients (IP) and 67.9% of out-patients (OP) with UTI were isolated with E. coli.

Key words: lower UTI, Uropathogens, Antibiotic susceptibility, In and out patients, South India.