Home|Journals|Articles by Year

Directory for Medical Articles

Original Research

RMJ. 2005; 30(1): 12-15

Ulcerative Colitis: Experience at a Tertiary Care Center

Nasir Khokhar.


Objective: Ulcerative colitis has a world-wide distribution but its prevalence and clinical patterns in Pakistan are not known. This study was performed to ascertain the clinical patterns of ulcerative colitis in patients referred to a tertiary care center.

Methods: All patients presenting with diarrhea, blood in stools and biopsy proven for ulcerative colitis were prospectively followed for clinical features, laboratory findings, endoscopic features and treatment response over the study period.

Results: A total of 85 patients were seen and followed for up to 8 years. All had diarrhea with blood in stools. All had numerous white blood cells in stool. Erythrocyte sedimentation rate was elevated in 94 % of patients. More than half had mild disease and distal colitis. All patients responded well to standard treatment with anti-inflammatory drugs.

Conclusion: Most patients of ulcerative colitis were mild in severity and had distal involvement. Clinical features in this cohort were similar to patients in most other parts of world. All responded to standard treatment. (Rawal Med J 2005; 30:12-15).

Key words: Ulcerative colitis, Inflammatory Bowel Disease, Flexible Sigmoidoscopy, Colonoscopy, Mesalazine, 5 ASA

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.