Background: Duodenal and Gastric perforations are one of the most common causes of peritonitis and
lead to major postoperative complications. If these post-operative complications are reduced, that can lead to an
improvement in morbidity and mortality. In Perforation because of peptic ulcer, different modalities of treatment varies
from conservative management, simple closure of ulcer, ulcer closure with omentum, jejunal serosal patch, definitive
treatment with truncal vagotomy and drainage procedures or parietal cell vagotomy, laparoscopic repair and NOTES
omental repair. Methods: The study was conducted in 60 patients of peptic ulcer perforation. Out of these 60 patients: 30
patients (group A) underwent Grahms patch repair with omentopexy, and other 30 patients (group B) underwent omental
plugging with omentopexy, and this procedure is different from modified Grahms patch. The outcome of procedures
was done in term of complication like bile leakage, wound infection, respiratory infection, intra-abdominal abscess, burst
abdomen/ gastric outlet obstruction and mortality. Results: Peptic ulcer perforation shows male predominance over
female. Was vividly demonstrated by incidence of 25 males (83.33%) and 5(16.66%) female in group A where as in Group
B incidence of disease was 24 males (80.0%) and 6 (20.0%) were females. No statistical difference between two groups.
Mean age in group A was 46.80 ± 13.9 years and group B was 48.60 ± 14.04 years. Biliary leak was seen in 4 cases of
Grahms patch with omentopexy whereas no leak was seen in omental plugging with omentopexy. Wound infection and
mortality were also significantly high in Grahms patch group in comparison to omental plugging with omentopexy.
Conclusion: Analysis of results of present study showed that omental plugging with omentopexy has tremendous scope
over Grahms patch with omentopexy in terms of morbidity and mortality.
Key words: Perforated peptic ulcer, Grahms patch, plugging, omentopexy