The current study was undertaken to evaluate the preclinical efficacy of methanolic extract of Eclipta alba (MEEA) against isoniazid and rifampicin (INH-RIF) induced hepatic injury. Animals were randomly divided in five groups, vehicle (control) or INH-RIF (50 mg/kg, i.p.) or MEEA (200 and 400mg/kg, p.o.) or standard silymarin for 28 days. INH-RIF intoxicated rats displayed significant (p
Key words: Eclipta alba, isoniazid, rifampicin, hepatotoxicity, oxidative stress, antioxidants
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