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Incidence of Early Left Ventricular Thrombus and Stroke After Acute Myocardial Infarction in the Primary Coronary Intervention Era Compared to Conservative Treatment

Lulzim S. Kamberi, Ahmet M. Karabulut, Hajdin R. Çitaku, Daut R. Gorani, Arton I. Beqiri.




Abstract

Background: Left ventricular thrombus is a well known complication of acute myocardial infarction. There are different data according to incidence of left ventricular thrombus in relation to the treatment of acute myocardial infarction. Objectives: The aim of this study was to further clarify theadvantages of one or the other method related to complications after acute myocardial infarction. Methods: This study was approved by the Committee of Ethics. Written informed consent was obtained from the patients prior to enrolment. This was prospective study performed in two different cardiologic centers in the same city, with different possibilities to treat acute myocardial infarction; one conservatively and another invasively. Four hundred consecutive patients with ST elevation acute myocardial infarction were accepted in the study during 2010. (200 patients per each center) respectively. Structural index, mean average, standard deviation, t-test and Chi2 were derived by SigmaStat and SPSS program. Results: No significant demographic data differenceswere found between two groups. Incidence of LVT were in PCI group 2% and 25% in non-PCI group, with significant difference (p≤0.0003). No patients with ischemic stroke were recorded in PCI group and 4% were found with strokes in non-PCI group or 16% in those with left ventricular thrombus of non-PCI group. Conclusions: PCI treatment is highly effective in reducing left ventricular thrombus compared to non-PCI treatment. Our data are in favor of aggressive treatment of acute myocardial infarction, resulting in fewer left ventricular thrombus and strokes.

Key words: left ventricular thrombus, myocardial infarction, stroke.






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