Home|Journals|Articles by Year|Audio Abstracts

Case Report

Intestinal Self Inoculation of Botulism in the ICU: Case Study and Literature Review of Intestinal Botulism with Emphasis on Dosing of Antitoxin

Kevin Verhoeff, Curtis Budden, Leah Remington, Shelley Duggan, Rajive Jassal.

Cited by 0 Articles

Botulism is a rare neuroparalytic disease requiring rapid identification and treatment. Foodborne toxaemia is well described but intestinal toxaemia is rare. Gastrointestinal (GI) abnormalities allow Clostridium botulinum to colonize the GI tract and release toxin systemically. Intestinal toxaemia has a unique protracted presentation with increased morbidity and mortality. Diagnosis is complicated by limited experience and conditions with similar symmetric descending paralysis.

Case Report:
We discuss intestinal toxaemia in a 48-year-old male with inflammatory bowel disease, who required a 140-day hospital stay including extensive intensive care management. We review the literature and outline the acute presentation, diagnosis, and empiric treatment with botulism antitoxin.

Intestinal toxaemia is a unique clinical entity with a protracted course and increased morbidity and mortality. Patients with GI abnormalities are at risk and early identification with empiric antitoxin treatment is crucial.

Key words: Botulism, Paralysis, Clostridium, Toxemia, Intestinal, Electromyography

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Refer & Earn
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.