Abstract

Background: It is generally accepted that the most serious complication of diabetes melitus is diabetic kidney disease. Diabetic kidney disease (DKD) is the leading cause of chronic and end-stage kidney disease and multiple complications including cardiovascular disease, infection, and death. Objective: The aim of our study was to detect the development and/or progression of the main complications related to diabetes, that are associated with the subsequent development of renal dysfunction. Methods: This prospective cohort study that included 97 participants with diabetes mellitus of both the genders mean age 58.3 ± 14.4 years, lasted for one year. Patients were divided into two groups: 74 with some form of chronic kidney disease (CKD) and 23 without CKD at baseline. CKD was defined as estimated glomerular filtration rate (eGFR)

Key words: Diabetes mellitus; Diabetic nephropathy; Chronic kidney disease; Albuminuria.