Abstract

Aim: Neutrophil-to-eosinophil ratio (NER) shows inflammation, which can play a role in the development of some epilepsies and ictogenesis. The current study aimed to investigate the NER and the variations in neutrophil and eosinophil levels in epilepsy patients with generalized tonic-clonic seizures.
Material and Methods: Epilepsy patients with generalized tonic-clonic seizures were retrospectively evaluated in the present study. Laboratory parameters of the patients in the acute (within 6 hours after the seizure) and subacute (on day 5 after the seizure) phases were compared.
Results: 60 patients (30 males and 30 females) who had generalized tonic-clonic epileptic seizures were included in the study. The median neutrophil count and NER were significantly higher in the acute phase than in the subacute phase (p

Key words: Eosinopenia; epilepsy; generalized tonic-clonic seizure; neutrophil-to-eosinophil ratio; neutrophilia