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A Clinical Study of Marjolin's Ulcer - An Avertible Tumor of Chronic Wounds and Scars - and Its Management in a Rural Tertiary Care Hospital

Ravi Hullamballi Shivaiah, Ravi Krishnappa, Naveen Narayan.

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Background: Marjolin's ulcer (MU), arising from chronic wounds and scars, is an aggressive malignancy which occurs after a latency period and can be potentially fatal. It has high risk of metastases and its management requires early diagnosis, well formulated treatment plan and prompt surgical intervention to ensure patient survival and quality of life. The purpose of this research is to study the clinical characteristics and management of MU at our tertiary center.
Methods: A prospective study of patients with MU who underwent treatment at our center between July 2016 and June 2021 was conducted. Demographic data, etiology of initial injury, latency period, lymph node metastasis, treatment and recurrence were analyzed.
Results: Out of 23 patients in study group, burns were the most common etiology of malignant degeneration (47.8%). The mean latency period was 5 years (IQR 3-8 years). Statistical analysis revealed a negative correlation between the age of patients at injury and the length of latency period (r = −0.652, P

Key words: Marjolin's Ulcer, Chronic Wound, Burns, Scar, Squamous Cell Carcinoma, Skin Grafting, Flap

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