Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Research

RMJ. 2020; 45(2): 287-290

Patterns of antibiotic susceptibility and resistance in some common wound pathogens from Sukkur, Pakistan

Fawad Shabbir Memon, Shaista Bano, Sarfraz Ali Tunio.

Objective: To investigate the trends in emerging antibiotic resistance among bacterial pathogens isolated from patients of wound infections from Sukkur district, Sindh.
Methodology: In this cross sectional, descriptive study, bacterial isolates were identified using microscopic and standard biochemical methods. In vitro, antibiotic susceptibility testing was carried out using Kirby-Bauer disc diffusion technique.
Results: A total of 48 bacterial isolates including Staphylococcus aureus (n=23) Pseudomonas aeruginosa (n=10), β-hemolytic streptococci (n=9), Escherichia coli (n=6), were recovered from different wound specimens. The Staphylococcus aureus had acquired resistance to penicillin (95.7%), methicillin (52.2%), while vancomycin remained the most effective antibiotic with 100% sensitivity rate followed by clindamycin (73.9%). Importantly, 83.33% Escherichia coli isolates were resistant to ceftazidime, ciprofloxacin, and 66.66% were resistant to aztreonam and cefipime while showing sensitivity to amikacin, imipenem and meropenem. In Pseudomonas aeruginosa isolates, high rate of resistance against gentamicin while sensitivity (90.0%) to polymyxin B was observed. Resistance to antibiotics in β-hemolytic streptococci was not profound.
Conclusions: The pathogens have acquired resistance to the frontline antibiotics emphasizing the need for antibiotic stewardship in Pakistan.

Key words: Wound infections, Staphylococcus aureus, Antibiotics, Bacterial infections, Drug resistance.

Similar Articles

Simultaneous preconcentration and determination of sulfonamide antibiotics in milk and yoghurt by dynamic pH junction focusing coupled with capillary electrophoresis.
Semail NF, Abdul Keyon AS, Saad B, Kamaruzaman S, Mohamad Zain NN, Lim V, Miskam M, Wan Abdullah WN, Yahaya N, Chen DDY
Talanta. 2022; 236(): 122833

A UHPLC/MS/MS method for the analysis of active and inactive forms of GLP-1 and GIP incretins in human plasma.
Villaño D, Zafrilla P, García-Viguera C, Domínguez-Perles R
Talanta. 2022; 236(): 122806

Understanding the Mechanisms of Gravity Resistance in Plants.
Soga K, Yano S, Kamada M, Matsumoto S, Hoson T
Methods in molecular biology (Clifton, N.J.). 2022; 2368(): 267-279

3D and 4D Tumorigenesis Model for the Quantitative Analysis of Cancer Cell Behavior and Screening for Anticancer Drugs.
Wessels D, Lusche DF, Voss E, Soll DR
Methods in molecular biology (Clifton, N.J.). 2022; 2364(): 299-318

Functional Characterization of Target Genes Associated with Insecticide Resistance of the Green Peach Aphid, Myzus persicae.
Fosu-Nyarko J, Iqbal S, Brigg F, Jones MGK
Methods in molecular biology (Clifton, N.J.). 2022; 2360(): 187-208

Full-text options

Latest Statistics about COVID-19
• pubstat.org

Add your Article(s) to Indexes
• citeindex.org

Covid-19 Trends and Statistics
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.

ScopeMed Web Sites