Background: undenatured type II collagen (UC-II®) have demonstrated its benefits in degenerative joint disease (DJD) management. Objective: exploratory clinical study to investigate the beneficial effects of, FLEXADIN-Advanced® in dogs. Methods: multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADIN-Advanced® during 6 months. Pain, overall general condition, appetite, mobility and lameness was assessed monthly by veterinarians and owners for 6 months. Compliance as was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance, p< 0.05). Results: parameters assessed were significantly lower comparing inclusion with at all subsequent months (P < 0.0001). Compliance at 3 months showed a good score but was significantly lower (P < 0.0001) at six months. Conclusion, FLEXADIN-Advanced®, containing UC-II®, can be considered a good complementary feed to provide joint support in dogs with mild to moderate DJD.
Key words: UC-II; dog; degenerative joint disease; supplement; compliance
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