Abstract

Background: Pseudoglucagonoma syndrome is an extremely rare disorder and refers to necrolytic migratory erythema (NME) in the absence of a glucagon-secreting tumor. Delayed diagnosis of glucagonoma might be attributed to the rarity of its incidence, which leads to its progression without treatment.
Case presentation: We report a case of a 45-year-old male presented with erythematous patches on the palms and soles, surrounded by hyperpigmented scaly borders. These started on the upper and lower extremities, then spread to the genitalia as erythematous crusted pustules and patches with sloughing of the skin and severe tenderness.
Conclusion: Improvement of these lesions was observed with improved nutrition.

Key words: Necrolytic migratory erythema (NME), pseudogluoconoma, nutritional deficiency, glucagonoma syndrome.