Original Article |
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SYNTHESIS AND SPECTRAL STUDIES OF NOVEL PYRIDINE,
PYRIDO[2,3-d]PYRIMIDINE AND PYRIDO[2,3-d]-3,1-
OXAZINE DERIVATIVESMahmoud R. Mahmoud, Hamed A. Derbala, Hassan M. F. Madkour, Mohamed M. Habashy, Mohamed H. Nassar. Abstract | | | | Several novel pyridine, pyrido[2,3-d]pyrimidine and pyrido[2,3-d] 3,1-oxazine derivatives were prepared using the readily obtainable
starting material 2-amino-6-aryl-4-(3,4,5-trimethoxyphenyl) pyridine-3-carbonitrile 1a,b via the reaction with one carbon donors such as
phenylisothiocyanate, carbon disulphide and formic acid. The IR, 1H-NMR and mass spectra for the new synthesized compounds were
discussed.
Key words: pyrido[2,3-d]pyrimidines, pyrido[2,3-d]-3,1-oxazines, one carbon donors.
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