Sickle cell disease (SCD) is considered as one of the most common genetic diseases. It causes an alteration in the shape and function of the red blood cells. In addition, hemolytic anemia and vascular occlusion areconsidered as the main clinical features of sickle cell. The study aimed at declaring the oral manifestations, considerations, and management of dental patients with SCD. A MEDLINE search was completed for the time period from 1990 to 2019 along with a manual search to locate relevant peer-reviewed articles and textbooks published in English. Several keywords were used to obtain all possible articles concerned with the subject. We obtained 25 articles; only 21 articles were specifically related to our subject. The study concludes that few studies have focused on studying the oral manifestations, dental considerations, and management of dental patients with sickle anemia and most of them were trials.
Key words: Sickle cell, oral manifestations, dental considerations, management
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