Objective: To determine the prevalence of pulmonary hypertension in patients with Chronic Liver Disease.
Methodology: This observational cross-sectional study was done in Department of Medicine, Jinnah Hospital, Lahore from 25th September 2017 to 25th March 2018. A total of 140 patients with chronic liver disease were enrolled. Demographic information was noted. All underwent echocardiography to diagnose pulmonary hypertension. Data were analyzed with SPSS 20.
Results: Of the 140 patients, 61.4% were male while 38.6% female. Mean age was 48.13+7.69 years. Family income up to Rs. 35,000/month was noted in 31.4% while more than 35,000 rupees per month in 68.6%. Diabetes was present in 37.1%. Child-Pugh Class B was seen in 58.6% while Child-Pugh class C in 41.4%. Mean body mass index was 28.21+4.21 kg/m2 and obesity was observed in 27.1%. Mean disease duration was 18.89+9.56 months. Smokers were 22.9%. Pulmonary hypertension was present in 15.0% participants. Severe pulmonary hypertension was seen in 3.6% whereas 11.4% had moderate pulmonary hypertension.
Conclusion: Pulmonary hypertension was prevalent in patients with chronic liver disease. It was associated significantly with diabetes mellitus, socioeconomic status, Child-Pugh class, smoking, disease duration and obesity.
Key words: Chronic liver disease, pulmonary hypertension, cirrhosis.