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High serum S-100B protein levels within the first 36 hours of acute ischemic stroke predicts high NIHSS scores

Tugba Yoruk Hazar, Bijen Nazliel, Asli Akyol Gurses, Hale Batur Caglayan, Ceyla Irkec.




Abstract
Cited by 1 Articles

Aim: The aim of the present study was to evaluate serum levels of S-100B which is an acidic calcium-binding protein within the first 36 hours following an acute ischemic stroke and to determine the correlation between S-100B levels and National Institutes of Health Stroke Scale (NIHSS) scores.
Material and Methods: Fifty patients with ischemic stroke (25 male, 25 female; mean age=64) and 30 healthy volunteers (14 male, 16 female; mean age=61) serving as age and sex matched controls were included in this study. Venous blood samples were taken within the first 36 hours following the acute stroke. The quantitative determination of S-100B in serum was carried out using an enzyme linked immunosorbent assay.
Results: Patients with acute ischemic stroke had significantly higher serum S-100B protein concentrations (42 pg/ml) than those of normal controls (31.5 pg/ml) (p

Key words: Cerebral infarction; stroke; S-100B Protein; S-100B Calcium Binding Protein beta Subunit






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