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RMJ. 2011; 36(2): 116-119

Low-dose Bupivacaine with fentanyl spinal anesthesia to prevent spinal-induced hypotension in adults

Mohammed Shawagfeh, Ahmad S Sbaihat, Essa A Mayyas, Ala D Alomari, Safwan G Fawaris.

To assess the usefulness and efficacy of low-dose Bupivacaine with Fentanyl spinal anesthesia for prevention of hypotension while maintaining good anesthetic conditions.
Patients and Methods
At Prince Rashid Hospital, 100 adult patients were randomized into two groups. The study group (F) comprised of 50 patients who received spinal anesthesia with Bupivacaine 7.5-9mg and fentanyl 25 g, while in control group (B), 50 patients received Bupivacaine 12.5-15mg only. The homodynamic stability of the patients and the quality of the blocks were compared.
All patients had adequate duration of reliable blocks. More control group patients than study group patients required ephedrine due to hypotension.
A reduced dose of Bupivacaine in combination with fentanyl provided reliable spinal anesthesia with few events of hypotension and little need for vasopressor support for blood pressure. (Rawal Med J 2011;36:116-119).

Key words: Bupivacaine, fentanyl, spinal anesthesia.

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