Objective
To compare the effects of oral clonidine and oral midazolam as preanesthetic medication in children during tonsillectomy.
Method
A double-blind randomized study was performed on 54 patients aged between 6 and 14 years who underwent tonsillectomy between September 2008 and May 2009 at King Hussein Medical City, Jordan. They were divided into two equal groups; in the 1st group oral midazolam (0.5 mg/kg) was administered 30 minutes before induction of anesthesia and in the 2nd group oral clonidine (4 µg/kg) was administered 90 minutes before induction of anesthesia. All were evaluated in the preoperative, intraoperative and postoperative period.
Results
Oral midazolam was superior to clonidine in relieving preoperative anxiety and shortening the time of separation from parents. Clonidine decreased the incidence of emesis and shortened the duration of surgery and anesthesia.
Conclusion
The clinical benefits of oral clonidine as preanesthetic medication outweighs the benefits of midazolam in children undergoing tonsillectomy and it should be recommended for use as prenesthetic medication. (Rawal Med J 2011;36:114-115).
Key words: Clonidine, midazolam, tonsillectomy.
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