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Original Article

ECB. 2013; 2(7): 481-484


AN EFFICIENT SYNTHESIS OF 4-ARYL-SUBSTITUTED 3,4- DIHYDROPYRIMIDIN-2(1H)-ONES USING NANOCOMPOSITE FERRITE CATALYST

Vijaykumar M. Joshi, Sanjay K. Vyawahare, Sunil U. Tekale, Sunita B. Shinde, Mohammed Fareesuddin, Satish A. Dake, Suresh U. Shisodia, Rajendra P. Pawar.


Abstract

A simple and efficient protocol has been reported for the synthesis of 5-ethoxycarbonyl-6-methyl-4-aryl-3,4-dihydropyrimidin-2(1H)-
ones using nanoparticulate ferrite composite as recyclable catalyst for one pot three component Biginelli reaction to afford the
corresponding product in excellent yields.

Key words: 3, 4-Dihydropyrimidin-2(1H)-ones, Ferrite composite, Multicomponent reaction.






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