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Original Research

RMJ. 2008; 33(2): 208-210

Blood transfusion is associated with increased resource utilization and bacterial infection

Mudassir Iqbal Dar, Ziauddin A Kashmiri, A Rasheed Khan, A Bari Khan, Atta ul Mannan, Asim Hassan Dar, Abdul Qadeer Khan, Rizwan A Memon, Khalil Almani, Mansoor Ahmad.


Objective: To observe the association of blood transfusion and clinical outcome in cardiac surgery patients.
Material and Methods: Forty patients underwent cardiac surgery during a period of two months in a single institution. Coronary artery bypass surgery (CABG) was performed in 21 (52.5%) patients, Mitral valve replacement (MVR) in 15 (37.5%) patients, aortic valve replacement (AVR) in 2 (5%) patients and Atrial septal defect (ASD) was closed in 2 (5%) patients. The mean age of the patients were 41.7±18 years, 80% were male.
Results: Twenty five (62.5%) patients required blood transfusion. Transfusion group showed chest wound infection (7.5%), pulmonary oedema (12.5%) and shortness of breath (10%). Total leukocyte count and platelets count were significantly lower in transfusion group.
Conclusion: We conclude that blood transfusion is associated with increased rate of infection and pulmonary oedema, with high cost and resource utilization. Blood transfusion should be used with appropriate caution. (Rawal Med J 2008;33:208-210).

Key words: Cardiac surgery, blood transfusion, clinical outcome

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