Home|Journals|Articles by Year|Audio Abstracts

Original Research

RMJ. 2007; 32(2): 146-149

Adenosine Deaminase Organic Effectors in Normal and Abnormal Cerebrospinal Fluid

Amina Hamed Ahmad Al& 8211;Obaidi, Abdul& 8211;Ghani Mohamed Ali Al& 8211;Samarai Abdul Monem Hamad Majed Al& 8211;Samarai.


Objective: To study the effect of the organic substances on adenosine deaminase
(ADA) activity in normal and abnormal cerebrospinal fluid (CSF).
Methods: Various concentrations of 2-mercaptopurine, Ame‚ÄĚtycine, Adenosine
analogues (Guanine, Thymine ) and ATP were tested to see their effect on ADA
activity in normal and abnormal CSF.
Results: ADA activity in normal and abnormal CSF was remarkably decreased with
the increasing of concentrations of substances tested.
Conclusion: These effects may have important therapeutic implications. (Rawal Med
J 2007;32:146-149).

Key words: Adenosine deaminase, CSF, Organic inhibitors, ATP, AMP.

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Refer & Earn
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.