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Study of visual evoked potentials in asymptomatic HIV-positive persons

Sharda Sangale, Mrunal Phatak.




Abstract

Background: Visual Evoked Potentials (VEPs) was studied in asymptomatic Human Immunodeficiency Virus (HIV) positive persons and corresponding controls to detect subclinical visual system involvement in the early stage of HIV.

Aim and Objectives: To study VEPs in asymptomatic HIV-positive persons and corresponding controls.

Materials and Methods: In this study,100 participants in the age group 25–45 years were recruited, fifty were HIV positive and asymptomatic (CD4 count >350 cells/mm3) and were not on Anti-Retroviral Treatment, and 50 were healthy age-matched individuals who were HIV negative.

Results: P 100 latency was significantly prolonged in the study group than in the control group. No significant difference was observed between the control group and study group for the amplitude of VEP.

Conclusion: Study of VEPs in asymptomatic HIV positive persons suggests subclinical visual nervous system involvement in early stages of HIV, as evidenced by prolonged P 100 latency. Hence, VEPs is important to detect subclinical nervous system involvement in the early stages of HIV.

Key words: Asymptomatic, Visual Evoked Potential, P 100 latency, HIV, Subclinical






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