Objectives: The aim of this study was measurment of Coronary
Sinus Blood Flow (CSBF) and Coronary Sinus Velocity time
Integral (CSVTI) via transthoracic echocardiography (TTE) in
patients with acute myocardial infarction (AMI) in association
with left ventricular ejection fraction (LVEF), wall motion
scoring index (WMSI) and in-hospital mortality.
Material and Methods: Twenty patients with anterior AMI and
20 healthy individuals as controls, were studied in 6 months
period in 2005 in Madani Heart Center in Tabriz, Iran. All
received same drugs for AMI treatment (e.g. fibrinolytic). CSBF,
CSVTI, WMSI and tissue Doppler imaging (TDI) data were
obtained via TTE and compared between the two groups.
Results: Baseline variables were similar between two groups
(p>0.05). CSBF in AMI group was 287.8 ± 128 ml/min and 415 ±
127 ml/min in control group (p=0.001). CSVTI was significantly
lower in AMI group than control group (11.16 ± 2.85 and 17.56 ±
2.72 mm, respectively; p = 0.003). There was significant correlation
between CSBF and LVEF (r = 0.52, p= 0.01), WMSI (r = -0.77, p =
0.0001) and in-hospital mortality (r=0.58 p= 0.03), also between
CSVTI and LVEF (r = 0.85, p = 0.0001), WMSI (r = -0.57, p =
0.0009) and in hospital-mortality rate (r = 0.69, p = 0.02). CSBF and
CSVTI had good correlation with TDI findings: Em (peak early
diastolic velocity in the myocardium) and Sm (peak systolic
velocity in the myocardium).
Conclusion: Our study demonstrated good correlation between
measured CSBF and CSVTI by 2D, Doppler TTE and LVEF,
WMSI, in-hospital mortality and also TDI findings; also we found
that CSBF and CSVTI were independent predictors in AMI
patients. (Rawal Med J 2007;32:112-117).
Myocardial infarction, transthoracic, echocardiography, oronary sinus,
wall motion scoring index, tissue doppler imaging.