The freshwater crab Potamonautes niloticus (Potamonautidae: Decapoda: Crustacea) is common in River Nile and its tributaries but has no commercial value as edible crab for human beings. So, the present study aims to evaluate the role of chitosan extracted from its exoskeleton for wound healing process as a medical application. The structure of chitosan has been physically investigated by using Fourier Transformer Infrared Spectroscopy (FTIR) to reveal the vibrational frequencies of different structural functional groups such as primary amine groups, hydroxyl groups and amide groups. Efficiency of the extracted chitosan was assessed by morphological and histological examination of wound healing in albino rats. Sections of isolated wounds were stained with hematoxylin and eosin to evaluate the histological changes during the wound healing process. Chitosan was yielded 30.64% from the crab shells and the results of wound healing assessments showed that the chitosan treated group (Ch 1%) was more efficient and faster than other groups (Ch 2, 3%) versus control groups. Also, the total leucocyte counts showed shortened inflammatory phase in chitosan treated groups. The present results showed the efficiency of extracted chitosan in wound healing process, and can be used in medical applications.
re-epithelization, inflammatory phase, chitin, crustacean shells
Gas phase ion-molecule reactions of nitroaromatic explosive compounds studied by hollow cathode discharge ionization-mass spectrometry.
Hong H, Habib A, Bi L, Wen L
Talanta. 2022; 236(): 122834
Controllable synthesis of uniform large-sized spherical covalent organic frameworks for facile sample pretreatment and as naked-eye indicator.
Li W, Wang R, Jiang HX, Chen Y, Tang AN, Kong DM
Talanta. 2022; 236(): 122829
Impact of pesticide formulation excipients and employed analytical approach on relative matrix effects of pesticide determination in strawberries.
Kasperkiewicz A, Lendor S, Pawliszyn J
Talanta. 2022; 236(): 122825
Cyclization and Self-Assembly of Cyclic Peptides.
MÃ©ndez-Ardoy A, Insua I, Granja JR, Montenegro J
Methods in molecular biology (Clifton, N.J.). 2022; 2371(): 449-466
Three Methods for Peptide Cyclization Via Lactamization.
Posada L, Serra G
Methods in molecular biology (Clifton, N.J.). 2022; 2371(): 3-17