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Original Research

RMJ. 2008; 33(1): 89-91

Prevalence of H. Pylori infection in patients with Gastroduodenal disease in Pakistan

Shah Sattar Khan, Asim Zulfiqar, K. F. Danish, Masood Sauwal, Shahid Bashir, Sharif-UZaman.

Objective: To ascertain the prevalence of Helicobacter pylori infection in gastroduodenal
diseases in Pakistan.
Methods: It was a prospective study carried out in a tertiary care referral centre for one
year. One hundred consecutive patients presenting with dyspeptic symptoms underwent
endoscopy for the diagnosis of gastroduodenal diseases and biopsies were taken for
histopathology and rapid urease test.
Results: Out of one hundred patients, 93 (93%) had chronic gastritis, one (1%)
adenocarcinoma and six (6%) had no pathology. Out of 93 patients with gastritis 11 had
duodenal ulcer, one had atrophic gastritis, and one had metaplasia. Prevalence of H. pylori
was 100% with duodenal ulcer and 84% with chronic gastritis.
Conclusion: Most of the patients presenting with dyspepsia had chronic gastritis and
among them 12% had duodenal ulcer. Eighty-four percent patients with
gastritis and 100% with duodenal ulcer had H. pylori infection. (Rawal Med
J 2008;33:88-90).

Key words: Acid peptic disease, gastritis, duodenal ulcer, H. pylori.

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