Bone metastases of breast cancer since recently, among others, are treated with Zolendric acid. Often in the world are mentioned necroses of mandible surrounding mucosa and oral cavity in such patients, with unproven causal relation. First time at the Department of Maxillofacial Surgery of the Clinical Center Sarajevo verified the two cases with the same pathology. Goal of this review is to show the social aspect of medical treatment of the mouth, which has great significance. Dilemmas are present, on how to treat, as surgically well as with medications. Results of treatment are not satisfactory since it stems to mutilate the patient, in terms of functional and aesthetic deficit, and that the duration is unfavorable for the community and patients. Open dilemma remains how to create algorithms (protocols of treatment and post surgical resocialization).
Key words: Bone metastases. Zolendric acid, Breasts cancer, Mandible necrosis, Resocialization.
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